Expert clinical trials statistical consultancy
At Aligns, we offer statistical consultancy for clinical trials, bringing extensive experience across diverse trial designs.
Our statistician is semi-retired and can use this time to work with Aligns. At Aligns we are a contracted service and not a co-applicant. Any funding submission that requires a statistical co-applicant should refer to their nearest/preferred UKCRC clinical trials unit.
Why Aligns?
Our statistical expertise can benefit all projects within the clinical trials landscape. Whether you are an academic institution, NHS Sponsor, small biotech firm or a large pharmaceutical company, we tailor our services to meet your specific needs quickly. It may be that senior statistical advice/confirmation from an independent source becomes a need, or there is a requirement to input at a senior level to ensure trial designs are robust. Working with Aligns can provide this advice.
Clients contracting with Aligns for clinical trials services can take advantage of enhanced trial efficiency by just getting things done when needed. Too many times we have heard ‘where is SAP ?’, ‘where is DMP?’ or ‘we need x document before we can progress with next stage’. Investigators need to be involved in the production of these documents, however, most don’t have the time or expertise to be fully involved. Trust is required which may only develop from a proven record of past experience. You can trust Aligns to facilitate the production of review-ready, trusted, essential documents for your trial.
Who?
Professor Alex McConnachie is Director of Biostatistics and Professor of Clinical Trial Biostatistics at the Robertson Centre for Biostatistics (RCB), University of Glasgow, where he also serves as Lead Biostatistician for the Glasgow Clinical Trials Unit — a UKCRC-registered unit comprising the RCB, the Glasgow Clinical Research Facility, and the NHS Greater Glasgow and Clyde R&I Division.
With over 30 years’ experience in the design, analysis, and reporting of randomised trials and other health studies, Professor McConnachie has been a central figure in clinical trials methodology at one of the UK’s most productive trials units. His statistical expertise spans a wide range of therapeutic areas including cardiovascular disease, mental health, child development, surgery, exercise, obesity, social deprivation, and health inequalities.
The Robertson Centre has led or contributed to many landmark trials in cardiovascular medicine, including WOSCOPS, PROSPER, IONA, CAPRICORN, BEAUTifUL, SHIFT, and EchoCRT. Professor McConnachie provides a key statistical leadership role across a large portfolio of trials. More recently he has provided trial biostatistics support on major trials including DiRECT (diabetes remission), PHoenix (pulmonary hypertension), and ALL-HEART (allopurinol and ischaemic heart disease), among many others across neurosciences, rehabilitation, and complex intervention research. With a current Google Scholar citation count exceeding 35,000, Professor McConnachie is a highly cited authority in clinical trial biostatistics.
In addition to his role as trial statistician, Professor McConnachie has served/serves as a member of Trial Steering Committees (TSCs) and Data Safety Monitoring Boards (DSMBs) / Independent Data Monitoring Committees (iDMCs) for trials conducted at other institutions, providing statistical oversight and independent statistical governance.
Professor McConnachie serves as a statistical reviewer for leading medical journals. His editorial contributions include Nature Medicine, PLoS Medicine, European Heart Journal and Heart.
